منابع مشابه
New drug in neoadjuvant chemoradiation for rectal cancer
Background: In recent years, neoadjuvant chemoradiation and subsequent surgical resection with total mesorectal excision has been shown to increase local control with decreased toxicity. Neoadjuvant chemoradiotherapy is the standard treatment for locally advanced rectal cancer. In this study we evaluated the efficacy a cox-2 inhibitor on pathologic response, sphincter preservation and acute tox...
متن کاملOptimal timing of computed tomography for assessing lymph nodes after neoadjuvant chemoradiotherapy for rectal cancer
Background: This study assessed the optimal timing of computed tomography for detection of metastatic disease in locoregional lymph nodes in patients with rectal cancer who have undergone chemoradiotherapy. Materials and Methods: This observational retrospective study was performed in a single institution. All patients with locally advanced rectal cancer treated with chemoradiotherapy, followed...
متن کاملTransanal endoscopic operation for rectal cancer after neoadjuvant therapy.
PURPOSE In this paper we report the oncological outcomes from clinical series of patients with rectal cancer submitted to local excision after neoadjuvant therapy and discuss the indications for local excision in partial clinical responders. METHODS We analysed a prospective database of 39 patients submitted to a transanal endoscopic operation for rectal cancer after neoadjuvant chemoradiatio...
متن کاملOptimizing neoadjuvant therapy for rectal cancer with oxaliplatin.
Neoadjuvant chemoradiation (CRT) is standard treatment for stage II-III rectal cancer. Fluoropyrimidine-based CRT prolongs disease-free survival over adjuvant CRT and improves local control over both adjuvant CRT and neoadjuvant radiotherapy alone, but does not prolong overall survival. New approaches to neoadjuvant therapy may improve outcome in this disease. Oxaliplatin, a standard component ...
متن کاملWatch and wait after neoadjuvant therapy for rectal cancer.
One of the most exciting, although contentious, areas of rectal cancer management in the past decade has been complete response after neoadjuvant chemoradiotherapy (CRT) with a ‘watch-and-wait’ policy in selected patients. Recent publications1–3 have added considerably to our knowledge on this complex topic, where sustained clinical, endoscopic and radiological response allows the consideration...
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ژورنال
عنوان ژورنال: Diseases of the Colon & Rectum
سال: 2018
ISSN: 0012-3706
DOI: 10.1097/dcr.0000000000001139